Study record

The Role of Peptide Hormones Discovered in the 21st Century in the Regulation of Adipose Tissue Functions

Kołodziejski PA, Pruszyńska-Oszmałek E, Wojciechowicz T et al. · Genes (Basel) · 2021

ReviewSeveralEvidence tier R
PubMed 34067710doi:10.3390/genes12050756Full text (PMC)Compare with another study

What this study reported

Reviewed nine peptide hormones, MOTS-c among them, and their reported roles in white and brown adipogenesis and energy homeostasis in cells and animals. MOTS-c is one item in a broad survey rather than the review's focus.

Limitations

Broad narrative review covering many unrelated peptides, with limited depth on MOTS-c and no systematic appraisal of the underlying studies.

Study record

Annotated fields for this study
Study modelReview
Substance studiedSeveralMore than one of these is central to the paper (common for reviews).
SpeciesNot reported
System studiedNarrative review of peptide hormones described since 2000 and their roles in white and brown adipose tissue
PopulationNot reported
DesignNarrative review
Sample size as reportedNot reported
Control groupNot reported
Route (data field only)Not reported
Endpoints measuredadipogenesis; energy homeostasis; brown adipose tissue function
Pathways measuredThermogenesis / brown fat · Lipid metabolism
Research areasMetabolic
Evidence tierR — Review (context, not evidence)
Publication typesJournal Article, Research Support, Non-U.S. Gov't, Review

Appraisal

Each dimension is recorded separately and never combined into a single score. A study can be well controlled and still tell you little about people.

Relevance to MOTS-c
Peripheral
Model applicability
n/a
Sample size
n/a
Controls
n/a
Outcome validity
n/a
Support for its own conclusion
Weak

Provenance

  • Bibliographic fields retrieved from PubMed E-utilities efetch (title, journal, date, authors, DOI) on 2026-11-11.
  • Annotated from the published abstract.
  • Editorial review: approved (2026-11-11).
  • Classification follows the site methodology; the record describes the study, not what MOTS-c does in people.