Editorial policy

Sources

• Study records come from PubMed. Bibliographic fields are retrieved programmatically, never typed by hand.
• Regulatory statements cite the regulator’s own documents, with the retrieval date recorded.
• Trial records come from ClinicalTrials.gov and are reproduced as the registry holds them.
• Molecular identity comes from UniProt, PubChem and AlphaFold DB, each named on the value it supports.
• Where only secondary reporting exists, the reference is marked as secondary and the gap is stated in the text.

What this site will not publish

• Doses, dosage charts, schedules, cycles, routes, injection or reconstitution instructions, or calculators.
• Conversions of experimental quantities from animal studies into human amounts.
• Claims that MOTS-c treats, prevents or cures any condition.
• Assertions that MOTS-c is safe, or that it has no side effects.
• Combination guidance, sourcing advice or purchasing recommendations.
• Pooled effect estimates across studies with different models, substances or endpoints.

These rules are enforced by an automated content check that runs over both the source files and the built pages. A build that breaks them fails rather than publishing.

How findings are written

The study is the subject of every sentence. A record says what a study reported in the system it used, and names that system in the same sentence. Directions of change follow the source exactly. Where an abstract is ambiguous, the record says what was measured rather than guessing at a direction.

Review and approval

Records carry an editorial review status that is visible on the page. Approvals are entered through a local-only tool and recorded in the repository with the reviewer and date; reviewer names are kept internal and are never rendered. A production build can be configured to fail on any unapproved citation it would render.

Corrections

Errors are corrected rather than quietly removed. If a cited study is retracted, its record is excluded from the evidence index and the exclusion reason is logged. If a regulatory position changes, the page is updated and re-dated. Every page shows when it was last reviewed. To report an error, see about.

Commercial relationships

Some pages carry a single contextual link to a related resource on an external commercial site. These links are tagged for attribution, are ordinary followed links, and never appear on the safety, dosage, regulatory, human evidence or legal pages. Product links require a completed legal review record before they can render at all; the build fails if that record is missing or contains placeholder text. No link changes how a study is classified or described.

Independence of the data

Study classification follows the published methodology and is applied the same way regardless of whether a finding is favourable. Negative, null and inconvenient results are indexed on the same terms as positive ones.

Policy last reviewed 2026-11-11.