Study record

MOTS-c attenuates endothelial dysfunction via suppressing the MAPK/NF-κB pathway

Li H, Ren K, Jiang T et al. · Int J Cardiol · 2018

ReviewEvidence tier R
PubMed 30041797doi:10.1016/j.ijcard.2018.03.031Compare with another study

What this study reported

No abstract is available; the title states that MOTS-c attenuates endothelial dysfunction via suppression of the MAPK/NF-κB pathway. Whether the letter reports original data cannot be determined from the record.

Limitations

Title-only record; study model, design and data cannot be assessed.

Study record

Annotated fields for this study
Study modelReview
Substance studiedNot reported
SpeciesNot reported
System studiedLetter/comment on MOTS-c and endothelial dysfunction (no abstract available)
PopulationNot reported
DesignLetter / comment
Sample size as reportedNot reported
Control groupNot reported
Route (data field only)Not reported
Endpoints measurednot reported
Pathways measuredMAPK signalling · Inflammation
Research areasCardiovascular
Evidence tierR — Review (context, not evidence)
Publication typesLetter, Comment

Appraisal

Each dimension is recorded separately and never combined into a single score. A study can be well controlled and still tell you little about people.

Relevance to MOTS-c
Direct
Model applicability
n/a
Sample size
Not reported
Controls
n/a
Outcome validity
n/a
Support for its own conclusion
n/a

Provenance

  • Bibliographic fields retrieved from PubMed E-utilities efetch (title, journal, date, authors, DOI) on 2026-11-11.
  • Annotated from the title only, because no abstract is indexed.
  • Editorial review: approved (2026-11-11).
  • Classification follows the site methodology; the record describes the study, not what MOTS-c does in people.